I’m beyond ecstatic to announce a new anonymous donor has come forward and is offering to match our total donations once we reach $100,000!
As of this writing, we’re sitting at $66,150, which means we have just $33,850 to unlock the match.
In other words, every $1 you contribute now is worth $4!
The Dream Scenario of 100 LMHRs
It was barely two months ago on the stage of Low Carb Houston that I announced the start of this project and that my dream scenario would be getting 100 Lean Mass Hyper-responders to participate. At 100, we’d have a very powerful population given the effect size reflected in their LDL levels.
Our back-of-the-envelope math suggests all the testing we wish to do (CT Angiogram, CIMT, CAC, etc) will probably be around $2,000 each. Thus, $200,000 gets us there.
Please Contribute and Share
We’ve come so far, so fast — but we couldn’t pull this off without your help. Please continue to contribute and share to help us cross that $100,000 line!
Tommy brings a wealth of experience and research aptitude that Spencer and I are quite excited to have onboard.
Tommy Wood’s Background
Tommy Wood is a Research Assistant Professor in the Pediatrics Department at the University of Washington. He received a bachelor’s degree in Natural Sciences and Biochemistry from the University of Cambridge before studying medicine at the University of Oxford. He worked as a junior doctor in central London for two years after medical school, and then moved to Norway to complete a PhD in physiology and neuroscience at the University of Oslo.
Tommy is currently President of Physicians for Ancestral Health, is a director of the British Society of Lifestyle Medicine, and is on the scientific advisory board of Hintsa Performance. Tommy has also coached and competed in multiple sports including rowing, CrossFit, powerlifting, and ultra-endurance racing. Alongside his career in medicine and research, Tommy has published and spoken on multiple topics surrounding lifestyle-based approaches to health.
Big Things Ahead, But We’re Not Allowed to Say Yet
The good news is that the LMHR Project may soon be getting upgraded into something much better with Tommy Wood’s help.
The bad news is that I can’t tell you what yet. The potential improvement requires that we follow specific rules, including our not talking about the process itself. I’ll simply say this will make sense once the initial part of this process is finalized, and I’ll be sharing it here when or if it is.
Update on Signing Up
IMPORTANT — we will not have a signup area for the LMHR Measurement Project for at least two or more months. The reason for this has to do with what I was explaining in the previous section. The direction we’re looking at will be very likely a big improvement, but it requires we don’t sign anyone up until a certain conditions are met first.
In the mean time, keep checking back here at the website for announcements as they develop. Thanks again for your patience!
The following is a roadmap I put together to help everyone get a sense of the intended scheduling.
This roadmap includes the documentary schedule as well, which will be substantial, particularly in January and February. We’ll be developing the project in parallel and getting it ready for a summer launch. I can’t announce too much on the specifics yet as we’re still in the designing stages.
Please Keep Sharing and Contributing!
We currently estimate around $2,000 in testing overhead expenses for each LMHR participant. Which means that as of this writing, we can fund nearly 33 total. But as I mentioned in Houston, I’d love if we could get to the magic number of 100. At that level, we’ll have a very sizable population given the effect size. I know it’s a stretch goal, but we’re already 1/3rd of the way there!
The process of putting it together in a hurry was extremely difficult. But to be fair, I really didn’t think we’d actually meet that goal in the first place! Once it was clear we were within striking range just a couple days before the race, I jumped into gear.
The following thread on twitter details the many foibles I ran into during the process. It’s quite a comical read:
1/ Massive costume thread…
Spoiler alert: A software engineer I am… I costume engineer, I am not. ?
I secretly started working on getting the costume together Friday morning as I figured if there were a 1% chance it could happen, I should at least be prepared… pic.twitter.com/XnjKC0uieE
The Citizen Science Foundation is seeking to advance “citizen science” by empowering those not formally trained in this field to connect with research evangelists, conduct rigorous scientific experiments, and promote shared data for the benefit of the scientific community.
Much of modern research is advanced through industry or academic study design and funding. Yet many ideas that help to advance science have historically been found across many disciplines and professions. The Trust is interested in making such ideas a reality through guidance, operation, and/or funding.
Lean Mass Hyper-responder Measurement Project
The Lean Mass Hyper-responder (LMHR) phenotype is characterized by LDL cholesterol of 200 mg/dL (5.17 mmol/L) or higher, HDL-C of 80 mg/dL (2.07 mmol/L) or higher, and Triglycerides of 70 mg/dL (0.79 mmol/L) or lower. We are likewise interested in “borderline” LMHRs that are near these same cut points.
We are seeking to help provide wide
spectrum blood panels and cardiovascular testing such as CT Angiogram, Carotid
Intima Media Thickness
and Coronary Artery Calcium (CAC) score to this phenotype of interest.
We further wish to encourage ongoing
communication and follow
participants, including a further set of measurements in five years.
With your support, we hope to gather data for at least 25 of these “hyper-responders”, but hope to meet our stretch goal of 100. We currently estimate costs for these tests to be between $1,000 to $2,000 and will cover wide spectrum blood tests as well as advanced physical testing such as CTA, CIMT, and CAC.
100% of proceeds will go toward testing and service costs for this project.
Again, we’re honored to have your consideration in helping us move this research forward. Thank you!